X9506-02
XRCC6 (X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 6, X-ray Repair Cross-complementing Protein 6, 70kD Subunit of Ku Antigen, ATP Dependent DNA Helicase 2 Subunit 1, ATP-dependent DNA Helicase II 70kD Subunit, CTC Box Binding Factor 75kD Subunit, CTC75, CTCBF, DNA Repair Protein XRCC6, G22P1, Ku 70, Ku70, Ku-70, Ku Autoantigen 70kDa, Lupus Ku Autoantigen Protein p70, ML8, Thyroid Lupus Autoantigen, TLAA, EC 3.6.1.-, X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6) (Azide Free)
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£685.00
- SKU:
- X9506-02
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to a portion of amino acids within aa1-610 of human Ku70 conjugated to glutathione S-transferase (GST).
- Klon:
- 4C2-1A6
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
- Weitere Details:
- The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq] Applications: Suitable for use in ELISA, Immunofluorescence, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1ug/ml-3ng/ml Western Blot: 1:500-1:1,000 Immunohistochemistry (paraffin): 1.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice