W1007-99-ML650

WDR77 (Methylosome Protein 50, MEP-50, WD Repeat-containing Protein 77, Androgen Receptor Cofactor p44, p44/Mep50, MEP50, WD Repeat Domain 77) (Azide Free) (MaxLight 650)

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£914.00

SKU:: W1007-99-ML650
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: 4°C Do Not Freeze
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to a portion of amino acids within aa1-343 of human WDR77.
Klon:: 3F10
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Weitere Details:: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).[supplied by OMIM] Applications: Suitable for use in FLISA, Immunohistochemistry (paraffin), and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:1,000 Immunohistochemistry (paraffin): 1.5ug/ml FLISA: 1ug/ml-3ng/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Versandbedingungen:: Blue Ice