U1000-17-PE

Ubiquilin (PE)

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£1,068.00

SKU:: U1000-17-PE
Reinheit:: Purified by Protein A affinity chromatography
Lagerbedingungen:: 4°C Do Not Freeze
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to the C-terminal region of the human ubiquilin protein
Klon:: 3B8A10
Format:: Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with R-Phycoerythrin (PE).
Weitere Details:: Ubiquilin is a recently discovered protein that is involved in early onset Alzheimer’s disease. Ubiquilin binds to and promotes aggregation of presenilin proteins. Although the ubiquilin protein contains ubiquitin-like domains, ubiquilin appears to increase presenilin synthesis, rather than affect presenilin turnover. Ubiquilin is found in neuropathological lesions that are characteristic of Alzheimer’s and Parkinson’s diseases. Applications: Suitable for use in FLISA and Western Blot. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.