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T8252-92

Transforming Growth Factor beta Induced (BIGH3, TGFBI, Beta-ig-h3)

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£642.00

SKU:
T8252-92
Reinheit:
Purified by immunoaffinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Goat
Immunogen:
Synthetic peptide corresponding to C-QLYTDRTEKLRPE, from the Internal region of human TGFBI. Species sequence homology: mouse, rat, canine.
Format:
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:32,000 Western Blot: 0.2-0.5ug/ml. ~70kD band observed in Human, Mouse and Rat Kidney lysates (calculated MW of 74.7kD according to Human NP_000349.1). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice