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T0297

TACC2 (Transforming, Acidic Coiled-coil containing protein 2, Anti-Zuai-1, AZU-1, ECTACC)

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£793.00

SKU:
T0297
Anwendung:
WB
Reinheit:
Purified by affinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Rabbit
Immunogen:
Linear peptide corresponding to the mature chain of mouse TACC2, conjugated to KLH. Species Sequence Homology: rat
Format:
Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide.
Weitere Details:
TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009). Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilutions: Western Blot: 2ug/ml detected TACC2 on 10ug of mouse testis tissue lysate Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb I1904-46Q: IgG, H&L (HRP) Pab Gt xRb Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice