S9299-95

Syntrophin (Syntrophin 1, Syntrophin-1, Syntrophin alpha 1, SNTA1, 59kD Dystrophin-associated Protein A1 Acidic Component 1, Dystrophin-associated Protein A1 59kDa Acidic Component, Dystrophin-associated Protein A1, Pro-TGF-alpha Cytoplasmic Domain-interacting Protein 1, SNTB1, SNTB2, TACIP1)

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£576.00

SKU:: S9299-95
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane. Epitope: Within the PDZ domain of syntrophin. Cellular Localization: Neuromuscular synapse.
Klon:: 9E784 (1351)
Format:: Supplied as a liquid in PBS, 0.1% BSA, 0.05% sodium azide.
Weitere Details:: Syntrophin (alpha-1) is a peripheral membrane protein located at the neuromuscular junction. Syntrophin (alpha-1) is expressed at high levels in skeletal muscle and heart, and at lower levels in brain, pancreas, liver, kidney and lung. It is an adaptor protein which is thought to bind and organise the subcellular localisation of membrane proteins such as utrophin and acetylcholine receptor. Syntrophin (alpha-1) also binds phosphatidylinositol 4,5-bisphosphate, it may link various receptors to the dystrophin glycoprotein complex and the actin cytoskeleton. Applications: Suitable for use in Flow Cytometry Immunofluorescence/Immunocytochemistry, Immunohistochemistry, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Immunofluorescence (IC): 1-2ug/ml Flow Cytometry: 0.5ug /10e6cells Western Blot: 0.1-1ug/ml. Detects a band at ~58kD representing syntrophin from rat and mouse cell extracts. Immunohistochemistry (paraffin, frozen): 1:10-1:500 Immunoprecipitation: 1:10-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice