S8091-18A

SSRP1 (FACT80, FACT Complex Subunit SSRP1, Chromatin-specific Transcription Elongation Factor 80kD Subunit, Facilitates Chromatin Transcription Complex 80kD Subunit, FACT 80kD Subunit, FACTp80, Facilitates Chromatin Transcription Complex Subunit SSRP1, Recombination Signal Sequence Recognition Protein 1, Structure-specific Recognition Protein 1, hSSRP1, T160)

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£429.00

SKU:: S8091-18A
Reinheit:: Purified by affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Partial recombinant protein corresponding to human SSRP1.
Klon:: 3E4
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Weitere Details:: SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT140 complex is composed of the Spt16 and the SSRP1 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. Applications: Suitable for use in Immunoprecipitation, Immunocytochemistry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml Immunocytochemistry: 2.5-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.