S7985-10

STYK1, NT (Tyrosine-protein Kinase STYK1, Serine/Threonine/Tyrosine Kinase 1, Novel Oncogene with Kinase Domain, Protein PK-unique, NOK)

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£696.00

SKU:: S7985-10
Reinheit:: Purified by ammonium sulfate precipitation
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the N-terminal region of human STYK1 (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: STYK1, a probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP kinase and phosphatidylinositol 3'-kinases (PI3K) pathways. It is widely expressed; highly expressed in brain, placenta and prostate. STYK1 is expressed in tumor cells such as hepatoma cells LO2, cervix carcinoma cells HeLa, ovary cancer cells Ho8910 and chronic myelogenous leukemia cells K562, but not in other tumor cells such as epidermoid carcinoma. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:250-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.