STAT3 (Signal Transducer and Activator of Transcription 3, Acute-Phase Response Factor, APRF)

Größe

£642.00

SKU:: S7971-02L
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to CRPESQEHPEADP, from human STAT3, at the internal region. Species sequence homology: mouse, rat and canine
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry, ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:16,000 Flow Cytometry: 10ug/ml Western Blot: 1-3ug/ml, observed in human heart and liver lysates, on ~75kD bands Immunohistochemistry (paraffin): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.