S5381
Spectrin, alpha (Spectrin Non-erythroid alpha Chain, Alpha Fodrin, Alpha II Spectrin, Spectrin alpha Non-erythrocytic 1, SPTAN1, SPTA2)
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£991.00
- SKU:
- S5381
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Chicken red blood cell membranes purified by hypotonic lysis and mechanical enucleation
- Klon:
- AA6
- Format:
- Supplied as a liquid in PBS, 1% BSA, 0.09% sodium azide.
- Weitere Details:
- Non-erythroid Spectrin, also known as Fodrin, plays a role in stabilizing membrane structures, maintaining cell shape and linking the cytoskeleton to plasma membranes or intracellular vesicles. As one of the primary targets cleaved by activated caspases during apoptosis, the full-length ~240kD protein can be cleaved to yield an N-terminal product of ~150kD, and C-terminal products of ~120 and ~35 kD. Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and ChIP. Other applications not tested. Recommended Dilutions: Immunohistochemistry (IFA): 1:200-1:400. Does not work on paraffin sections. Western Blot: 1:500 detected N-, C- terminal Spectrin alpha/Fodrin alpha on 10ug of staurosporine treated HeLa lysates. Optimal dilutions to be determined by the researcher. Positive Control: HeLa cells treated with staurosporine Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice