S1013-72N

SIK2 (Serine/Threonine-protein Kinase SIK2, Qin-induced Kinase, Salt-inducible Protein Kinase 2, SIK-2, Serine/Threonine-protein Kinase SNF1-like Kinase 2, KIAA0781, QIK, SNF1LK2)

Größe

£486.00

SKU:: S1013-72N
Reinheit:: Purified by affinity chromatography
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to human SIK2
Klon:: S15G10
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Weitere Details:: SIK2 (Salt inducible kinase 2) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and AMP-activated protein kinase (AMPK) subfamily, predicted molecular weight 104kD. SIK2 is found in adipocytes and might be involved in metabolic regulation in adipose tissue. Sik2 phosphorylates ser794 of human insulin receptor substrate-1 (IRS1) in insulin-stimulated adipocytes, playing important roles in modulating the insulin-signaling cascade of adipocytes. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Western Blot: 1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.