S1013-65B
Siglec 11 (Sialic Acid-binding Ig-like Lectin 11, Sialic Acid-binding Lectin 11, Siglec 11, UNQ9222/PRO28718) (PE)
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£709.00
- SKU:
- S1013-65B
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Goat
- Immunogen:
- Recombinant protein corresponding to Asn17-His543 (Glu84Ala, Lys145Gln) from human Siglec-11 expressed in a CHO cell line.
- Format:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
- Weitere Details:
- Siglecs are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-set domain which mediates sialic acid binding, followed by a varying numbers of Ig-like C2-set domains. Siglec-3 and Siglecs-5-13 constitute the CD33/Siglec-3 related group, which are defined by their sequence homology and differential expression in the hematopoietic system. In humans, Siglec-11 is expressed in tissue macrophages, brain microglia, and inflammatory site monocytes. Strong microglial expression is specific to humans, as it is less prominent or absent in chimpanzees and orangutans. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: Neat. 10ul labels up to 1x10e6 cells. Optimal dilutions to be determined by the researcher. Excitation: 488nm Emission: 565-605nm Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
- Versandbedingungen:
- Blue Ice