S0630-05B
IgA Secretory Component (Secretory Component Glycoprotein, Secretory Component p85, Extracellular Matrix Protein 1, ECM1, ECM-1)
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£576.00
- SKU:
- S0630-05B
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Secretory Component from human colostrum.
- Klon:
- SC-05
- Format:
- Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
- Weitere Details:
- Secretory Component Glycoprotein is an epithelial transport receptor for polymeric IgA and IgM. Antibody to secretory component has been shown to be useful for identifying glandular carcinomas. Defects in Secretory Component Glycoprotein are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness. Histologically, there is widespread deposition of hyaline material and disruption/reduplication of basement membrane. Applications: Suitable for use in Immunohistochemistry, Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Immunohistochemistry (Frozen and paraffin sections): 2-8ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice