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  2. Monoclonal

S0095-30

SAP97 (Synapse-associated Protein 97, Discs Large Homolog 1, DLG1, dJ1061C18.1.1, DKFZp761P0818, DLGH1, HDLG, Presynaptic Protein SAP97)

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£326.00

SKU:
S0095-30
Reinheit:
Purified by Protein G affinity chromatography from ascites.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Mouse
Immunogen:
Recombinant protein corresponding to rat SAP97 (N-Terminal fragment).
Klon:
4E202
Format:
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
Weitere Details:
Synapse-associated proteins SAP97 and SAP102 display extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminals. In addition to the CNS, SAP97 is also detected at the basal lateral membrane between a variety of epithelial cells. SAP102 associates with NMDA receptors through the C-terminal NR2B subunit of the receptor. The N-terminal SAP97 PDZ domain mediates its interaction with the synaptic ras-GTPase activating protein SynGAP. Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry and Electron Microscopy. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 (ECL). Detects bands at ~97kD and 140kD. Optimal dilutions to be determined by researcher. Positive Controls: Rat Brain Tissue Extract, Mouse Brain Tissue Extract Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice