Retinoic Acid (all-trans Retinoic Acid, Vitamin A Acid, ATRA, Tretinoin)

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£165.00

SKU:: R1690-01E
Molekulargewicht:: 300.44
Reinheit:: 98-102% (HPLC)
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
CAS Number:: 302-79-4
Format:: Yellow to light orange lyophilized powder.
Weitere Details:: Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation. Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons. Synonyms: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; Tretinoin; all-trans-Retinoic acid, ATRA; Vitamin A acid; 15-Apo-beta-caroten-15-oic acid; Aberel; Avita; Retin-A; Retinova; Isotretinoin EP Impurity A CAS No: 302-79-4 Molecular Formula: C₂₀H₂₈O₂ Molecular Weight: 300.44 Appearance: Yellow to light orange lyophilized powder. Purity: 98-102% (HPLC) Solubility: Chloroform, DMSO, Methanol (Sparingly) Loss on Drying: ≤0.5% Melting Point: 168-170˚C Sulfated Ash: ≤0.1% Heavy Metals: ≤0.002% Limit of Isotretinoin: ≤5% Storage and Stability: Powder may be stored at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light and temperature sensitive. Keep under inert atmosphere

Versandbedingungen:: Blue Ice