R1032-01A

RAIDD, Recombinant Human (RIP-associated ICH-1, CED-3-homologous protein with DD, CRADD, Caspase and RIP adapter with DD)

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£512.00

SKU:: R1032-01A
Anwendung:: WB
Molekulargewicht:: 24.9
Reinheit:: Purified: ≥95% by SDS PAGE.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Format:: Supplied as a liquid in 20mm tris, pH8.0, 20% glycerol.
Weitere Details:: CRADD is a 22kD, widely-expressed cytosolic adaptor protein. CRADD is a death domain (CARD/DD) containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain- containing proteins. Source: Recombinant human CRADD fused in his tagged expressed in E. coli (1-199aa). AA Sequences: MGSSHHHHHH SSGLVPRGSH MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLMLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE Storage and Stability: Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.