P9544-01B
PDX1, CT (Pyruvate Dehydrogenase Protein X Component, Mitochondrial, Dihydrolipoamide Dehydrogenase-binding Protein of Pyruvate Dehydrogenase Complex, Lipoyl-containing Pyruvate Dehydrogenase Complex Component X, E3-binding Protein, E3BP, PDHX)
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£696.00
- SKU:
- P9544-01B
- Reinheit:
- Purified by ammonium sulfate precipitation
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide selected from selected from the C-terminal region of human PDX1 (KLH).
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Weitere Details:
- PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice