Proteolipid Protein (PL)P (HLD1, Lipophilin, MMPL, Myelin proteolipid protein, PLP, PLP/DM20, PMD, SPG2)

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£806.00

SKU:: P4283-02A
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Chicken/Avian
Immunogen:: Synthetic peptide corresponding to a region of the Proteolipid Protein gene product, conjugated to KLH. Species Sequence Homology: human (PLP1 isoform 1 and PLP1 isoform 2 and mouse.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Weitere Details:: Human PLP (also known as lipophilin) is a 29.946 kD protein (277 aa) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in its compaction. Different mutations of the human PLP gene product result in two neurological disorders -- Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2. Applications: Suitable for use in Immunohistochemistry, Immunocytochemistry and Western Blot. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry (Frozen): 1:1000-1:5000 Immunocytochemistry: 1:2000-1:5000 Western Blot: 1:2000-1:5000 Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1906: IgY, Chicken Pab Rb x Ch I1906-10: IgY, Chicken (HRP) Rb x Ch I1906-12: IgY, Chicken (FITC) Rb x Ch I1906-14: IgY, Chicken (AP) Rb x Ch Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice