N8350-01D
NUMB (h Numb, h-Numb, Numb Homolog, Numb Protein Homolog, Protein S171, S171)
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£594.00
- SKU:
- N8350-01D
- Anwendung:
- WB
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653). Homology: The immunogen used for this antibody production has 100% homology with mouse, human and chicken (isoforms 1-4) proteins and 90% homology with rat numb protein (isoforms unknown).
- Format:
- Tris-glycine and 150 mM NaCl
- Weitere Details:
- Numb is an evolutionarily conserved membrane-associated protein. It exists in four isoforms that differ in two functional domains: a phosphotyrosine-binding (PTB) domain and a proline-rich region (PRR). It plays a role in the control of cell fate decisions during development and antagonizes the actions of Notch. Numb proteins appear to control the self-renewal of all neural progenitor cells and could possibly play similar roles in stem-cell maintenance in other tissues. Cellular Localization: Membrane-associated Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice