N5375-03M
Notch-1 (9930111A19RIK, hN1, LIN12, Lin-12, MIS6, Neurogenic Locus Notch Homolog Protein 1, NOTC1, Notch (Drosophila) Homolog 1 (Translocation Associated), Notch 1 Extracellular Truncation, Notch 1 Intracellular Domain, Notch Homolog 1, Notch Homolog 1 Translocation Associated (Drosophila), Translocation Associated (Drosophila), Translocation Associated Notch Homolog, Translocation Associated Notch Protein TAN1) (PE)
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£735.00
- SKU:
- N5375-03M
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- NS0-derived, recombinant protein corresponding to Ala19-Gln526 from human Notch-1.
- Klon:
- 9H168
- Format:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
- Weitere Details:
- Notch-1 (so named for “notches” in fly wings; also TAN-1) is a 300kD, 2538aa member of the Notch family of type I TM glycoproteins. It is associated with gene activation in both embryo and adult. It undergoes Golgi processing to generate a heterodimer composed of a 180-200kD disulfide-linked extracellular domain (aa18-1664), and a 120kD membrane-bound segment (aa 1665-2556) that is cleaved to form the notch intracellular domain transcription factor upon ligand binding. Human Notch-1 ECD (aa19-526), including the first 13 EGF repeats, shows 91% aa identity with corresponding regions of mouse and rat Notch-1, and 60% aa identity with human Notch-2 and Notch-3. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.j
- Versandbedingungen:
- Blue Ice