N1192
NETO1 (Neuropilin (NRP) and Tolloid (TLL)-like 1, BCTL1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor Class A domains protein 1, BTCL1, Neuropilin and Tolloid-like Protein 1)
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£774.00
- SKU:
- N1192
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Thr23-Val345 from human NETO1 expressed in CHO cells.
- Klon:
- 9L847
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Weitere Details:
- Neuropilin and tolloid-like protein 1 (NETO1), also known as Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 (BTCL1), is a type I transmembrane protein that is expressed in the brain and retina. The 511aa residue mature human NETO1 contains an extracellular domain with two CUB domains (aa41-155 and 172-287), and one class A LDL-receptor segment (aa292-326). Three human NETO1 splice isoforms exist, including a secreted soluble variant that shows an Asp-to-Glu transition at residue 157 followed by a premature truncation. over aa23-345, human NETO1 shares 97% and 98% aa identity with mouse and canine NETO1, respectively. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 25ug/ml detects NETO1 in paraffin-embedded normal human cortex sections. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice