NASH1 (SAM Domain-containing Protein SAMSN-1, Hematopoietic Adaptor Containing SH3 and SAM Domains 1, SAM Domain, SH3 Domain and Nuclear Localization Signals Protein 1, SH3-SAM Adaptor Protein, SAMSN1, HACS1)

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£642.00

SKU:: N0046-15A
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to IRLDTLSASLGRSC, from human SAMSN1, at N-terminal (NP_071419.2).
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:: Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.5-1.5ug/ml, observed in Jurkat Tcell lysate on ~48kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.