M4700-11P

Mucin 1 (Mucin-1, MUC1, MUC-1, Breast Carcinoma-associated Antigen DF3, Carcinoma Associated Mucin, CD227, DF3, Episialin, Epithelial Membrane Antigen, EMA, H23 Antigen, H23AG, KL-6, MAM6, Peanut-reactive Urinary Mucin, PUM, Polymorphic Epithelial Mucin, PEM, PEMT, Tumor Associated Epithelial Membrane Antigen, Tumor-associated Mucin)

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£843.00

SKU:: M4700-11P
Reinheit:: Purified
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: MUC1 60mer tandem repeat NH2-(VTSAPDTRPAPGSTAPPAHG)3-COOH conjugated to BSA.
Klon:: VU-13F11
Format:: Supplied as a liquid in PBS, 0.05% sodium azide.
Weitere Details:: MUC-1 is a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The extracellular domain of MUC1 largly consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is upregulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.