M3007-14-ML650
c-Met, CT (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) (MaxLight 650)
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£615.00
- SKU:
- M3007-14-ML650
- Reinheit:
- Purified
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide derived from the human c-Met C-terminus sequence, conjugated to a carrier protein. Expected Staining Pattern: Cytoplasmic
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™650.
- Weitere Details:
- MaxLight™ 650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. c-MET (HGFr) is a proto-oncogene (locus 7q21-q31) protein and a cell-surface receptor of hepatocyte growth factor. It has tyrosine kinase activity. It consists of alpha (50kD) and beta (145kD) subunits linked by a disulfide bond. c-Met is overexpressed in many cancers. The MET gene is often amplified between tumorgenesis and metastasis. It has been suggested that c-Met is useful as a prognostic marker in numerous cancers including: breast cancer, gastric carcinoma, endometrial carcinoma and others. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen and formalin-fixed paraffin-embedded sections. Epitope retrieval required using citrate buffer, pH 6.0 is required. Enzyme digestion is not required. Optimal dilutions to be determined by the researcher. Positive Control: Breast carcinoma Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice