M2420-66-BIOTIN
Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A) (Biotin)
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£889.00
- SKU:
- M2420-66-BIOTIN
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- E. coli-expressed active rat 72kD type IV collagenase (catalytic domain)
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
- Weitere Details:
- The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP 2. MMP-2 (72kD type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Optimal dilution determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice