Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A) (APC)

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£889.00

SKU:: M2420-66-APC
Reinheit:: Purified by Protein A affinity chromatography.
Lagerbedingungen:: 4°C Do Not Freeze
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: E. coli-expressed active rat 72kD type IV collagenase (catalytic domain)
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Weitere Details:: The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP 2. MMP-2 (72kD type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling. Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilutions: Optimal dilution determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.