M2420-57
Matrix Metalloproteinase 2 (MMP-2, Collagenase IV, Gelatinase A)
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£819.00
- SKU:
- M2420-57
- Reinheit:
- Purified
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic oligopeptide corresponding to aa468-483, VTPRDKPMGPLLVATF of human Matrix Metalloproteinase 2.
- Klon:
- 2Q520 (42-5D11)
- Format:
- Supplied as a liquid in 0.1M PBS, pH 7.0, 2% BSA (protease free).
- Weitere Details:
- MMPs each have different substrate specificities within the ECM and are important in its degradation. MMP-2 mainly degrades type IV collagen and denatured collagens. MMP activity is modulated by tissue inhibitors of metalloproteinases (TIMP). Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by TIMP have been implicated in the invasive potential of malignant tumors. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1-5ug/ml Immunohistochemistry (Paraffin using PLP fixation): 1-5ug/ml Not tested in traditional formalin fixed tissues. Immunohistochemistry (Frozen): 0.9ug/ml Optimal dilution determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice