M2363-19N

MAP Kinase Kinase 5 (Dual Specificity Mitogen-activated Protein Kinase Kinase 5, Map2k5, MAPKK 5, Mkk5, Prkmk5, MAPK/ERK Kinase 5, MEK 5, Mek5)

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£320.00

SKU:: M2363-19N
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to a portion of human MEK5. The sequence is completely conserved in rat.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Weitere Details:: The MAP kinase kinase (Mek) protein kinase family is upstream of, and thus responsible for, the activation of the MAP kinases by phosphorylation of threonine and tyrosine residues. Mek5 is a 49kD kinase and is responsible for the tyrosine phosphorylation and activation of Erk5 (1). Mek5 contains unique amino acid sequences in its amino terminus which suggest this protein may interact with GTPases such as cdc42 (1). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1,000, ECL Optimal dilutions to be determined by researcher. Positive Controls: Mouse Brain Tissue Extract Rat Brain Tissue Extract Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.