M2351-80A

MAP Kinase 1 (Mitogen-activated Protein Kinase 1, MAPK 1, MAPK1, ERT1, Extracellular Signal-regulated Kinase 2, ERK2, ERK-2, ERK, MAP Kinase Isoform p42, Mitogen-activated Protein Kinase 2, MAP Kinase 2, MAPK 2, MAPK2, p41mapk, p42-MAPK, P42MAPK, PRKM1, PRKM2)

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£404.00

SKU:: M2351-80A
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Human p42 ERK2 c-terminal peptide (KLH).
Format:: Supplied as a liquid in TBS, 0.09% sodium azide.
Weitere Details:: MAPK is a 42kD member of the serine/threonine protein kinase family. MAPK is also known as extracellular-signal regulated kinase (ERK) and is an important integration point of many signalling pathways. It modulates gene transcription in the nucleus in response to changes in the cellular environment, controlling a range of cellular processes including proliferation, differentiation, transcription regulation and development. MAPK is also thought to be important in learning and memory. When phosphorylated, activated MAPK translocates to the nucleus, where it phosphorylates nuclear targets. Applications: Suitable for use in ELISA, Western Blot, and Immunoprecipitation. Other applications not tested. Recommended Dilution: ELISA: 0.5ug/ml Western Blot: 1ug/ml Immunoprecipitation: 5ug/sample Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.