L1565-02B

Lck, p56 (Lymphocyte-specific Tyrosine Kinase)

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£812.00

SKU:: L1565-02B
Reinheit:: Purified by Protein G affinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: E. coli-derived recombinant human Lck (aa1-66) UniProt # P06239
Klon:: 7H125
Format:: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.
Weitere Details:: Lymphocyte-specific protein-tyrosine kinase (Lck), also known as p56 Lck and Lsk, is a member of the Src family of non-receptor tyrosine kinases. First identified as a gene rearranged and overexpressed in murine lymphomas, lck behaves as a proto-oncogene and its activation can lead to cellular transformation. Lck protein is anchored to the plasma membrane and interacts with the intracellular domains of CD4/CD8 coreceptors in T lymphocytes. Applications: Suitable for use in Immunocytochemistry and ELISA. Other applications not tested. Recommended Dilution: Immunocytochemistry: 25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.