LAMA3 (Laminin Subunit alpha-3, Epiligrin 170kD Subunit, E170, Epiligrin Subunit alpha, Kalinin Subunit alpha, Laminin-5 Subunit alpha, Laminin-6 Subunit alpha, Laminin-7 Subunit alpha, Nicein Subunit alpha, LAMNA)

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£448.00

SKU:: L1227-60D
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to NNQCHSSHKRRTK, from LAMA3, at the internal region of the protein (NP_937762.1).
Format:: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Weitere Details:: Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.