L1100-01K
LAIR-1 (Leukocyte-associated Ig-like Receptor-1) (APC)
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£787.00
- SKU:
- L1100-01K
- Anwendung:
- Flow Cytometry
- Reinheit:
- Purified by Protein A affinity chromatography from hybridoma culture supernatant.
- Lagerbedingungen:
- 4°C Do Not Freeze
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Gln22-His163 from human LAIR1 isoform 1 expressed in NS0 mouse myeloma cell line
- Klon:
- 7H26
- Format:
- Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
- Weitere Details:
- LAIR1 is an inhibitory receptor belonging to the Ig superfamily. It is a type I transmembrane protein with one extracellular Ig-like domain and two cytoplasmic ITIMs. Four LAIR1 splice variants exist. LAIR1b has a 17aa deletion outside the Ig loop in the extracellular domain. It differs from LAIR1c by one amino acid residue. LAIR1d has a 77aa truncation in the cytoplasmic domain. LAIR1 is expressed on NK cells, T cells, B cells, monocytes, dendritic cells and most thymocytes. The extracellular domain of human LAIR1 shares 40% amino acid identity with that of the mouse protein. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels/10e6 human peripheral blood lymphocytes Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
- Versandbedingungen:
- Blue Ice