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I7662-89Q

Interferon Regulatory Factor 6 (IRF6)

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£642.00

SKU:
I7662-89Q
Reinheit:
Purified by peptide affinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Goat
Immunogen:
Synthetic peptide corresponding to C-TPSMQLPPALPPQ, from the C Terminus of human IRF6 (NP_006138.1).
Format:
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:1:32,000 Immunohistochemistry: 2-3ug/ml in paraffin embedded Human Kidney shows strong nuclear staining in DCT and glomerulus Western Blot: 0.2-0.6ug/ml; ~60kD band observed in Human Ovary lysates (calculated MW of 53.1kD according to NP_006138.1). In transfected HEK293 transiently expressing IRF6 a band of approx. 55kD is observed. This band is not observed in the non-transfected HEK293 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice