I7661-30

Integrin, alpha1

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£819.00

SKU:: I7661-30
Reinheit:: Purified by Protein A affinity chromatography
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Purified human Integrin alpha 1.
Klon:: 0.T.63 (5E8D9)
Format:: Supplied as liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride.
Weitere Details:: Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metastatic and invasive potential of tumor cells. Alpha1 associates with beta1, and the resulting heterodimeric cell-surface receptor recognizes collagen and laminin. The inserted von Willebrand factor type I domain in the alpha1 subunit is thought to be involved in collagen binding. Applications: Suitable for use in Immunocytochemistry and Neutralization. Other applications have not been tested. Recommended Dilutions: Immunocytochemistry: cold ethanol fixed cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.