I7661-19M

Insulin-Like Growth Factor I Receptor, NT (IGF-I Receptor, IGFIR, IGFR, Insulin-like Growth Factor 1 Receptor, IGF1R, CD221, JTK13, MGC18216, MGC142170, MGC142172)

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£696.00

SKU:: I7661-19M
Reinheit:: Purified by ammonium sulfate precipitation
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the N-terminal region of human IGF1R (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.