H1830-48M

Heat Shock Protein 22 (HSP22, H11, E2IG1, HSPB8, Heat shock protein beta-8, E2-induced gene 1, spinal muscular atrophy, distal, adult, autosomal dominant, small stress protein-like protein HSP22, protein kinase H11, hereditary motor neuropathy, distal, heat shock 27kD protein 8, Charcot-Marie-Tooth disease, spinal, HMN2A, HMN2, DHMN2, CMT2L)

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£642.00

SKU:: H1830-48M
Anwendung:: WB
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide aa184-196, NELPQDSQEVTCT, from C-terminal human Hsp22.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:: HSPB8 (heat shock protein beta-8), otherwise known as HSP22, a monomeric protein and member of the small heat shock protein (HSP20) family, which displays temperature dependent chaperone activity. HSPB8 is predominantly expressed in the heart and skeletal muscle, and defects in HSPB8 are responsible for the neuromuscular disorder distal hereditary motor neuronopathy type 2A (HMN2A), and the axonal CMT neuropathy Charcot Marie Tooth disease type 2L (CMT2L). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: ~20-25kD band seen in Human Muscle lysate [Predicted MW of ~22kD according to NP_055180]. Optimal dilutions to be determined by the researcher. Positive Control: Human Muscle lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.