G8956-02
Granzyme A
Größe
£863.00
- SKU:
- G8956-02
- Reinheit:
- Purified by Protein G affinity chromatography from hybridoma culture supernatant
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to Cys26-Val262 from human Granzyme A, expressed in NS0 cells.
- Klon:
- 7H129
- Format:
- Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Weitere Details:
- Granzyme A, also known as CTLA-3, is the most abundant serine protease found specifically in the cytotoxic granules of cytotoxic T lymphocytes and NK cells. It is released during cellular activation and enters target cells through perforin channels. Granzyme A mediates target cell killing by inducing caspase-independent cell death. Human granzyme A is synthesized as a precursor with a signal peptide, a two amino acid propeptide, and a mature chain. Mature human granzyme A shares 71% amino acid sequence identity with mouse granzyme A. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1ug/ml ELISA: Direct Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice