G-Protein Coupled Receptor 68 (GPR68, GPR12A, MGC111379, OGR-1, OGR1, Ovarian cancer G-protein coupled receptor 1, Sphingosylphosphorylcholine receptor)

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£646.00

SKU:: G8600-72C
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to a18 amino acid peptide from 1st extracellular domain of human GPR68. Species Sequence Homology: gorila, gibbon, marmoset, 100%, mouse, bat, canine, hamster, panda, equine, porcine. 94%; bovine, rabbit, platypus 89%; elephant 83%
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Weitere Details:: OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). OGR1 has been reported to be expressed in blood, brain, heart, kidney, lung, placenta, small intestine, spleen, and testis. ESTs have been isolated from blood, lung, and uterine libraries. Caution: OGR1 is also known as GPR12A, which is distinct from GPR12 in cluster 3851. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (FFPE): 10-20ug/ml. Heat-induced antigen retrieval in citrate buffer, pH 6.0 is recommended. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice