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G2033-63

GGCX (Gamma-glutamyl Carboxylase, GC, FLJ26629, Vitamin K-dependent gamma-carboxylase, Vitamin K gamma Glutamyl Carboxylase, VKCFD1)

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£642.00

SKU:
G2033-63
Reinheit:
Purified by peptide affinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Goat
Immunogen:
Synthetic peptide corresponding to C-PPESNPDPVHSE, from the C-Terminus of human GGCX (NP_000812.2; NP_001135741.1).
Format:
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:
This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Peptide ELISA Titer: 1:32,000 Western Blot: 0.3-1ug/ml detects ~85kD band observed in Human Muscle lysates (calculated MW of 85kD according to NP_000812.2). Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice