G2005-02-APC

Ganglioside GD2 (Disialoganglioside GD2) (APC)

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£1,075.00

SKU:: G2005-02-APC
Reinheit:: Purified by Protein A affinity chromotography from cell culture supernatant.
Lagerbedingungen:: 4°C Do Not Freeze
Hersteller:: United States Biological
Host:: Mouse
Immunogen:: Human neuroblastoma cell line.
Klon:: 2Q549
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Weitere Details:: GD2 has been identified as tumor-associated antigens expressed on the surface of neuroectoderm-derived tumors (melanoma, neuroblastoma and glioma) and T-cell leukemia. Gangliosides (sialic acid-containing glycosphingolipids) are normal membrane constituents and highly expressed in the vertebral central nervous system. Applications: Suitable for use in Immunofluorescence/Immunocytochemistry, Flow Cytometry, Immunohistochemistry and Cytotoxicity. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: Frozen tissue sections Immunofluorescence: Cells in culture Cytotoxicity: GD2 positive cells Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.