FOXP2 (Forkhead Box P2, Forkhead Box Protein P2, CAG Repeat Protein 44, CAGH44, SPCH1, Trinucleotide Repeat-containing Gene 10 Protein, TNRC10)

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£642.00

SKU:: F9050-02J
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-DEVEYQKRRSQKIT, from the internal region of human FOXP2. Species sequence homology: Bovine, canine, feline, mouse and porcine.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. It plays a role in the differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Defects in FOXP2 are the cause of speech-language disorder 1 (SPCH1); also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Affected individuals have a severe impairment in the selection and sequencing of fine orofacial movements, which are necessary for articulation. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.3-1ug/ml. ~85kD band observed in Human Brain (Cerebellum and Frontal Cortex) lysates and in Rat Brain lysates (MW 82.6kD). Immunohistochemistry (Paraffin): 2-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice