F4305-08-HRP
Fibroblast Growth Factor Receptor beta (Flg, FGFRb, FGFR1) (HRP)
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£1,055.00
- SKU:
- F4305-08-HRP
- Reinheit:
- Purified by affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Bovine Fibroblast Growth Factor Receptor beta purified from Coronary Venular Endothelial Cells (CVEC).
- Klon:
- 3G150
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with horseradish peroxidase (HRP).
- Weitere Details:
- Currently four FGF receptors have been identified, FGFR-1 (flg), FGFR-2 (bek), FGFR-3, and FGFR-4. FGFR-1 and FGFR-2 exist in multiple forms that represent alternative splicing of their respective genes. The FGF Receptor consists of three immunoglobulin-like domains, a transmembrane region and a cytosolic tyrosine kinase domain which is activated by ligand binding. FGFs play important roles in angiogenesis, wound healing, tumorigenesis and metastasis. The FGF family consists of 7 members, FGF-1 through FGF-7. FGFs 1 and 2 are also known as basic FGF (bFGF) and acidic FGF (aFGF), respectively. It is known that multiple FGFs can bind and activate FGFR-1, FGFR-2, and FGFR-3. Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Paraffin sections Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0/Ag14 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Versandbedingungen:
- Blue Ice