F4150-13H
FK506 Binding Protein 2, aa22-142, Recombinant, Human (FKBP2, FKBP-2, 13kD FK506-binding Protein, 13kD FKBP, FKBP13, FKBP-13, Immunophilin FKBP13, Peptidyl-prolyl Cis-trans Isomerase FKBP2, PPIase FKBP2, Rotamase)
Größe
£607.00
- SKU:
- F4150-13H
- Anwendung:
- WB
- Molekulargewicht:
- 13.4
- Reinheit:
- ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Format:
- Supplied as a liquid in 20mM Tris buffer, pH 8.0, 1mM DTT, 10% glycerol.
- Weitere Details:
- FKBP2 is peptidyl proline isomerase enzyme and a member of the immunophilin protein family. This protein is predominantly expressed in thymus and T cells and plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Recombinant FKBP2 protein was expressed in E. coli. Source: Recombinant corresponding to aa22-142 of human FKBP2 expressed in E. coli. AA Sequence: MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL Enzyme Activity: Specific activity is > 700 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmol of suc-AAFP-PNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice