F3965-07A
FEZ2, CT (Fasciculation and elongation protein zeta 2, HUM3CL, MGC117372, Pre-T/NK cell-associated protein 3Cl, Zygin-2, Zygin II)
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£655.00
- SKU:
- F3965-07A
- Anwendung:
- WB
- Reinheit:
- Purified by immunoaffinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to 15aa from near the carboxy terminus of human FEZ2 (Genbank accession No. NP_001036013).
- Format:
- Supplied as a liquid in PBS, 0.02% sodium azide.
- Weitere Details:
- Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76 (1,2). In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-ζ substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-ζ, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-ζ in a tissue non-specific manner (1). FEZ2 can interact with FEZ1 through its c- terminal regions and especially its coiled-coil region (5). At least two isoforms of FEZ2 are known to exist. Applications: Suitable for use in Western Blot Other applications not tested. Recommended Dilution: Western Blot: 0.5–1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice