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D9831-01B

CYBRD1 (Cytochrome B Reductase 1, Duodenal Cytochrome B, Ferric-chelate Reductase 3, DCYTB, FRRS3)

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£642.00

SKU:
D9831-01B
Reinheit:
Purified by immunoaffinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Goat
Immunogen:
Synthetic peptide corresponding to CRNLALDEAGQRSTM at the C-terminal, from human CYBRD1 (NP_079119.3). Species Sequence Homology: bovine, canine and porcine
Format:
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:
Ferric-chelate reductase that reduces Fe3+ to Fe2+. Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe3+ thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA (Peptide): 1:16,000 Western Blot: 0.1ug/ml using human colon lystates showed bands at 35kD, 26kD and 28kD. Immunohistochemistry (Paraffin): 2-5ug/ml using human testis shows membranous staining in primarily myofibroblasts of the basement membrane surrrounding the seminiferous tubules. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice