DLL3 (Delta-like Protein 3, Drosophila Delta Homolog 3, Delta3)

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£607.00

SKU:: D2727-85A
Reinheit:: Purified by Protein A affinity chromatography
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa100-150 of human DLL3. Species Sequence Homology: feline; 83%, bovine; 81%, rat; 72%
Format:: Supplied as a liquid in PBS, 0.05% sodium azide
Weitere Details:: Delta-like protein 3 is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 3-5ug/ml Immunohistochemistry (Paraffin): 5ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Mouse embryo brain, T98G (human) cell lysate, human brain Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Versandbedingungen:: Blue Ice