C8350-08D
CXCR4 (Fusin, LESTR, C-X-C Chemokine Receptor 4, CD184)
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£704.00
- SKU:
- C8350-08D
- Reinheit:
- Purified by affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to aa14-40, YSEEVGSGDYDSNKEPCFRDENVHFNR of the N-terminal extracellular domain of mouse CXCR4 (CXC chemokine receptor 4)
- Format:
- Supplied as a liquid in PBS, 1mg/ml BSA, 0.09% sodium azide.
- Weitere Details:
- CXCR4, also termed Fusin, LESTR, or HUMSTR is a member of the G-protein-coupled chemokine receptor family with seven membrane spanning domains and functions as a coreceptor for X4 HIV-1 entry into CD4+ cells. CXCR4 is expressed predominantly on naïve T cell subset of peripheral blood and is rapidly upregulated by PHA and IL-2 stimulation. It is also expressed on neutrophils, monocytes and various cell lines. C8350-08D binds to CXCR4 receptor on mouse spleen leukocytes as determined by immunocytochemistry. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:500 Immunohistochemistry (Paraffin): 1:200 on mouse spleen cells. ELISA: 1:25,000 Immunocytochemistry: on mouse spleen cells. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Versandbedingungen:
- Blue Ice