C8350-06B
CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184)
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£442.00
- SKU:
- C8350-06B
- Reinheit:
- Purified by Protein A affinity chromatography.
- Lagerbedingungen:
- -20°C
- Hersteller:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- E.coli-expressed N-terminal rat CXCR4, aa2-38
- Format:
- Supplied as a lyophilized powder, 0.09% sodium azide. Reconstitute with 200ul sterile ddH2O.
- Weitere Details:
- CXCR4 (fusin) is a members in the seven-transmembrane domain G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library1. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been shown to be the co-receptor for HIV-1 binding to CD4 through the viral envelope glycoprotein gp1202. In other cases, CXCR4 can function as the only receptor for the interaction of HIV-2 with CD4 and host cells3. A mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium. Applications: Suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry and Neutralization. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Versandbedingungen:
- Blue Ice