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C7904-82W

COX 2 (PTGS2, Prostaglandin-endoperoxide synthase 2 (Prostaglandin G/H synthase and cyclooxygenase), COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, Prostaglandin G/H synthase and cyclooxygenase)

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£642.00

SKU:
C7904-82W
Reinheit:
Purified by immunoaffinity chromatography.
Lagerbedingungen:
-20°C
Hersteller:
United States Biological
Host:
Goat
Immunogen:
Synthetic peptide corresponding to sequence C-NPTVLLKERSTEL, from the C-terminal of human COX 2. Species sequence homology: canine, bovine and porcine
Format:
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Weitere Details:
COX2 (Cyclooxygenase 2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX2 is therefore of interest in studying immune response regulation. COX2 is induced by a wide variety of stimuli and was initially identified as immediate early growth response gene. In addition, COX2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX1 levels remain unchanged. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:32,000. Western Blot: 0.1-0.3ug/ml Flow Cytometry: 10ug/ml Immunofluorescence: 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Versandbedingungen:
Blue Ice