Contactin-3 (CNTN3,(plasmacytoma associated) BIG-1, Brain-derived immunoglobulin superfamily protein 1, Contactin-3, KIAA1496, PANG, PCS, Plasmacytoma-associated neuronal glycoprotein)

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£832.00

SKU:: C7865-23
Reinheit:: Purified by immunoaffinity chromatography.
Lagerbedingungen:: -20°C
Hersteller:: United States Biological
Host:: Goat
Immunogen:: NS0-derived, recombinant mouse Contactin-3 aa20-1003; Q07409.
Format:: Supplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
Weitere Details:: Contactin-3 (also BIG-1 in rat and PANG in mouse) is a 150kD member of the TAG/F3 subgroup, contactin family, Ig superfamily hierarchy. It is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. Its exact function is unclear, but it likely mediates cell-cell interaction and may promote neurite outgrowth. Human Contactin-3 preproprecursor is 1028aa in length. It contains a 19aa signal sequence, a 983aa mature region and a 26aa cleavable C-terminal prosegment. The mature region shows six C2- type IG-like domains (aa26-593), followed by four fibronectin type III modules (aa598- 992). There is one potential alternate start site at Met128. Over aa26-992, human Contactin-3 shares 92% aa identity with mouse Contactin-3. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.5-1.0ug/ml Western Blot: 1.0ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Versandbedingungen:: Blue Ice